Tonari no Onee-san Episode 1 introduces viewers to Masahiko, a young man haunted by the fragmented memory of his ideal woman. Determined to preserve his virginity until he reunites with her, Masahiko's resolve is tested as he becomes the object of affection for several women in his life. At work, his alluring boss seeks companionship during her husband's absence, while at home, his voluptuous childhood friend moves in, igniting old feelings. College life further complicates matters, with both a seductive professor and a mysterious student expressing interest in him. Amidst these temptations, his neighbor, Asuka, harbors her own secret desires for him. The episode delves into themes of desire, memory, and the challenges of fidelity, blending humor and eroticism. The animation captures the sensuality and comedic undertones of Masahiko's predicaments, setting the stage for a narrative that explores the complexities of human relationships and the pursuit of idealized love.